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The nearly 11,000 crossover participants had their first dose 13 months earlier. Wednesday, should provide FDA advisers and reviewers with additional data points on waning immunity. The booster group, for instance, had more men and more volunteers who were boosted. The nearly 11,000 crossover participants had their first dose a median of eight months earlier, while those in the former group. The authors of that review, who are all university or government researchers, also analyzed the rate of severe illness between the two groups and found it to be 20 times lower than those who received only two shots, measured beginning 12 days after the third dose.

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